Building the Missing Infrastructure for Clinical Trial Activation
Clinical trials don't fail at the science. They fail at activation — the maze of regulatory compliance, site readiness, and document orchestration between protocol and First Patient In. That infrastructure didn't exist. We're building it.
Make First Patient In Predictable
NexTrial exists to compress the activation bottleneck — the 60–120 day maze between protocol design and first patient enrollment. We build orchestration intelligence that makes trial startup predictable, audit-ready, and jurisdiction-aware across FDA, ANVISA, and CDSCO. We don't replace the humans in the loop. We give them the infrastructure to move with confidence.
Own the Clinical Trial Workflow
Trial Activation Intelligence gets you to First Patient In. Trial Execution Intelligence carries you to First Patient Out. Celina orchestrates both — calmly, predictably, explainably. Our long-term objective is workflow ownership: the system sponsors trust to start trials, the layer CROs rely on to stay on track, and the intelligence regulators can audit.
The Team
Operators, not observers. Every person on this team has built, shipped, or regulated in clinical research.
Steven Thompson
Founder & CEO
20 years building systems in regulated industries. 7 in clinical and pharmaceutical operations at Biogen and Takeda. Led a $1.2B enterprise transformation at ADM and scaled NuBank through a regulated IPO. Designed and built NexTrial's architecture — LangGraph orchestration, physics-informed neural networks, and a regulatory foundation model — after watching sponsors lose millions to an activation problem no one was solving. His thesis: every patient is a differential equation, and the maze was never necessary.
Graziela Peduti
Head of Global Regulatory Intelligence
Leads all Brazil and ANVISA engagement. Regulatory peer to institutional partners. Architect of NexTrial's multi-jurisdiction compliance framework across FDA, ANVISA, and CDSCO.
Omkar Mirajkar
Regulatory Intelligence, India
Builds and maintains NexTrial's India regulatory intelligence alongside Graziela Peduti. Third chair on every rule review before it reaches Celina. Extends NexTrial's engagement with India's biotech and registry ecosystem.
Manminder Singh
Founding Engineer, AI Systems
Co-authored the functional specifications that define how Celina reasons about protocols and site readiness. Turns operational requirements into buildable, testable architecture. Owns the discipline that specs are durable and code is disposable.
Yan Barros
Senior Physics AI Engineer
Physics and machine learning architecture. Builds the computational core that lets Celina model trial activation as a system rather than a checklist. Leads engineering on NexTrial's next-generation eligibility work.
Advisory Board
Alexandra Laymon
GTM & Commercial Strategy Advisor
Category language architect and commercial co-builder. Owns sponsor, CRO, and investor journey strategy.
Javier Granados II, PharmD
Academic & Site Network Lead
Oncology pharmacist and clinical operations specialist. Leads academic partnerships and site network engagement.
Dr. Michelle Purdom
BioTech & Sponsor Strategy Advisor
Co-architect of NexTrial's buyer scenario framework. Deep biotech sponsor lens for resource-constrained trial programs.
Stacey Carden
Quality Advisor
Brings a quality and user-experience lens to how Celina is built and how buyers move through it. Pressure-tests the product against the standard of the people who will inspect it.
Daniel Guerra
Brazil Design Council
Represents the site and research operations perspective on NexTrial's Brazil Design Council. Validates that what Celina produces works in Portuguese, in Brazilian institutions, for the teams who run trials there.
Provably Right, Not Probably Right
Protocol
CFM-1 Regulatory Engine
Jurisdiction Blueprints
Audit-Ready Packets
FDA · ANVISA · CDSCO
Deterministic verification, not confidence scores. Every regulatory decision has a traceable lineage. Every packet is validated against jurisdiction-specific requirements before submission.
Our Plugin Boundary Covenant
We will never store a document. We will never capture a data point. Celina orchestrates — your systems govern storage, your teams own decisions, patients stay protected. This isn't a policy. It's architecture.
DIA 2026 Annual Meeting
Philadelphia · June 14–18, 2026
Abstract ID 116114 · Track 02
We'd rather present evidence than press releases.
Celina orchestrates. Humans decide. Patients get access.
Presented at DIA 2026 · Philadelphia · June 2026 · Abstract 116114