Building the Missing Infrastructure for Clinical Trial Activation
Clinical trials don't fail at the science. They fail at activation — the maze of regulatory compliance, site readiness, and document orchestration between protocol and First Patient In. That infrastructure didn't exist. We're building it.
Make First Patient In Predictable
NexTrial exists to compress the activation bottleneck — the 60–120 day maze between protocol design and first patient enrollment. We build orchestration intelligence that makes trial startup predictable, audit-ready, and jurisdiction-aware across FDA, ANVISA, and CDSCO. We don't replace the humans in the loop. We give them the infrastructure to move with confidence.
Own the Clinical Trial Workflow
Trial Activation Intelligence gets you to First Patient In. Trial Execution Intelligence carries you to First Patient Out. Celina orchestrates both — calmly, predictably, explainably. Our long-term objective is workflow ownership: the system sponsors trust to start trials, the layer CROs rely on to stay on track, and the intelligence regulators can audit.
The Team
Operators, not observers. Every person on this team has built, shipped, or regulated in clinical research.
Steven Thompson
Founder & CEO
20 years building systems in regulated industries. 7 in clinical and pharmaceutical operations at Biogen and Takeda. Led a $1.2B enterprise transformation at ADM and scaled NuBank through a regulated IPO. Designed and built NexTrial's architecture — LangGraph orchestration, physics-informed neural networks, and a regulatory foundation model — after watching sponsors lose millions to an activation problem no one was solving. His thesis: every patient is a differential equation, and the maze was never necessary.
Graziela Peduti
Head of Global Regulatory Intelligence
Leads all Brazil and ANVISA engagement. Regulatory peer to institutional partners. Architect of NexTrial's multi-jurisdiction compliance framework across FDA, ANVISA, and CDSCO.
Jeremy Jordans Garcia Flores
Founding ML Engineer
Computational physicist and machine learning engineer. Former atmospheric scientist at INPE Brazil. Brings physics-informed modeling discipline to clinical trial intelligence systems.
Advisory Board
Alexandra Laymon
GTM & Commercial Strategy Advisor
Category language architect and commercial co-builder. Owns sponsor, CRO, and investor journey strategy.
Javier Granados II, PharmD
Academic & Site Network Lead
Oncology pharmacist and clinical operations specialist. Leads academic partnerships and site network engagement.
Dr. Michelle Purdom
BioTech & Sponsor Strategy Advisor
Co-architect of NexTrial's buyer scenario framework. Deep biotech sponsor lens for resource-constrained trial programs.
Yan Barros
Founding Technical Advisor
Physics and ML architecture. Evaluates and shapes NexTrial's core computational infrastructure.
Dr. Alex Lee
IP & Regulatory Strategy Advisor
Manages NexTrial's patent portfolio and regulatory IP strategy across multiple jurisdictions.
Dr. Allan Freedline
Clinical & Medical Advisor
Medical credibility layer for CMO and VP Medical engagement. Bridges clinical practice and trial operations.
Provably Right, Not Probably Right
Protocol
CFM-1 Regulatory Engine
Jurisdiction Blueprints
Audit-Ready Packets
FDA · ANVISA · CDSCO
Deterministic verification, not confidence scores. Every regulatory decision has a traceable lineage. Every packet is validated against jurisdiction-specific requirements before submission.
Our Plugin Boundary Covenant
We will never store a document. We will never capture a data point. Celina orchestrates — your systems govern storage, your teams own decisions, your patients stay protected. This isn't a policy. It's architecture.
DIA 2026 Annual Meeting
Philadelphia · June 14–18, 2026
Abstract ID 116114 · Track 02
We'd rather present evidence than press releases.
Celina orchestrates. Humans decide. Patients get access.
Presenting at DIA 2026 · Philadelphia · June 14-18